This page explains how Gonal-F (follitropin alfa) is used in IVF treatment. All information is educational. Talk to your doctor about your specific protocol and any questions or concerns about your medications.
Overview
| Brand name | Gonal-F, Gonal-F RFF |
|---|---|
| Generic name | follitropin alfa |
| Category | Gonadotropin |
| How it is given | subcutaneous injection |
| Common dosages | 75 IU, 150 IU, 225 IU, 300 IU, 450 IU |
| Typical timing | Days 2 to 12 of stimulation phase |
What to expect: common side effects
Side effects vary from person to person. Many people experience only mild effects while others find them more significant. All of these experiences are valid. Report any severe or unexpected symptoms to your care team right away.
- Injection site redness or bruising
- Bloating and pelvic fullness
- Mood changes and irritability
- Mild headaches
- Breast tenderness
- Nausea
- Ovarian hyperstimulation syndrome (OHSS) in some patients
Storage instructions
Store unopened pens in the refrigerator between 2C and 8C (36F to 46F). Once opened, store at room temperature below 25C (77F) and use within 28 days. Keep away from light and heat.
Traveling with Gonal-F
Carry in a cool bag with ice packs for flights. Gonal-F pens are allowed through airport security as a medical necessity. Bring a letter from your doctor and keep medications in your carry-on bag, never in checked luggage. Request a cool-room storage option at your hotel if refrigeration is limited.
Tips from the IVF community
These are practical suggestions shared by people who have been through IVF. They are not a substitute for your clinic's guidance.
- Rotate injection sites (left abdomen, right abdomen) to reduce bruising
- Let the pen warm to room temperature for 15 minutes before injecting
- Ice the injection site for 30 seconds beforehand to reduce discomfort
- Log your dose time in TrackMyIVF immediately after injecting
- Tell your doctor about any significant bloating, as it may signal OHSS
- Your feelings about daily injections are valid. Many people find the routine difficult.
Track this medication with TrackMyIVF
Set dose reminders, log side effects, and share your medication timeline with your care team. TrackMyIVF keeps everything in one place so you never miss a dose.
Learn about TrackMyIVFFrequently Asked Questions
What is Gonal-F used for in IVF?
Gonal-F (follitropin alfa) is a gonadotropin used during the ovarian stimulation phase of IVF. It contains follicle-stimulating hormone (FSH), which encourages multiple follicles to grow in your ovaries so more eggs can be retrieved. Your doctor will decide whether Gonal-F is right for your protocol.
How do I inject Gonal-F?
Gonal-F comes as a pre-filled pen that is injected subcutaneously (just under the skin) in the abdomen or thigh. Your IVF clinic will show you exactly how to use the pen before your cycle begins. Always follow your clinic instructions, and call them if you have any questions.
What does Gonal-F feel like?
Most people find the injection itself is a quick pinch. Over the course of stimulation, you may notice bloating, pelvic pressure, and mood changes as your ovaries respond to the medication. Mild discomfort is normal, but severe pain or rapid weight gain should be reported to your doctor right away.
Can I miss a dose of Gonal-F?
Contact your clinic immediately if you miss a dose. Do not double up without guidance, as timing is carefully calibrated to your cycle. This is one reason many patients use TrackMyIVF to set dose reminders.
How long does a Gonal-F cycle last?
The stimulation phase typically lasts 8 to 14 days. Your doctor will monitor you with ultrasound and blood tests and adjust your dose as needed.
Medical disclaimer: This page provides general educational information only. It is not medical advice and should not replace guidance from your doctor, nurse, or reproductive endocrinologist. Every person's treatment is unique. Always consult your care team before making any decisions about your medications or treatment plan.
Get medication tips in your inbox
Practical guides for managing IVF medications, from someone who has been there.
No spam. Unsubscribe anytime.
Track your medications with confidence
Log every dose, set reminders, and share your schedule with your care team.
Explore Medication Tracking→Get medication tips in your inbox
Practical guides for managing IVF medications, from someone who has been there.
No spam. Unsubscribe anytime.
About the author
Viv
BSc, Patient Advocate
Founder, TrackMyIVF
I built TrackMyIVF because I needed it during my own journey. Every feature comes from real experience.