This page explains how Ovidrel (choriogonadotropin alfa) is used in IVF treatment. All information is educational. Talk to your doctor about your specific protocol and any questions or concerns about your medications.
Overview
| Brand name | Ovidrel |
|---|---|
| Generic name | choriogonadotropin alfa |
| Category | Trigger Shot |
| How it is given | subcutaneous injection |
| Common dosages | 250 mcg (standard trigger dose) |
| Typical timing | Single injection given approximately 34 to 36 hours before egg retrieval |
What to expect: common side effects
Side effects vary from person to person. Many people experience only mild effects while others find them more significant. All of these experiences are valid. Report any severe or unexpected symptoms to your care team right away.
- Injection site reactions
- Bloating and pelvic pressure (often already present from stimulation)
- Nausea
- Headache
- Risk of OHSS, especially in high responders
Storage instructions
Refrigerate between 2C and 8C (36F to 46F). Keep in the original packaging. Do not freeze. Once removed from refrigerator, use within 30 days if stored below 25C (77F).
Traveling with Ovidrel
Keep refrigerated until needed. Ovidrel is a single-use pre-filled syringe, which makes it straightforward to transport. Keep it in a cool bag and declare as medical necessity at security.
Tips from the IVF community
These are practical suggestions shared by people who have been through IVF. They are not a substitute for your clinic's guidance.
- The trigger shot timing is critical. Set multiple alarms and confirm the exact time with your clinic.
- Ovidrel is a subcutaneous injection, making it easier to self-administer than intramuscular alternatives
- After the trigger shot, you may notice increased bloating as your body prepares for retrieval
- Log the exact time of your trigger shot in TrackMyIVF. Your retrieval is scheduled based on this.
- The day of the trigger shot is a significant milestone. It is okay to feel a mix of hope, fear, and everything in between.
Track this medication with TrackMyIVF
Set dose reminders, log side effects, and share your medication timeline with your care team. TrackMyIVF keeps everything in one place so you never miss a dose.
Learn about TrackMyIVFFrequently Asked Questions
What does the Ovidrel trigger shot do?
Ovidrel contains a form of hCG (human chorionic gonadotropin) that mimics the natural LH surge. This triggers the final maturation of your eggs and initiates ovulation. Your doctor schedules egg retrieval approximately 34 to 36 hours after you inject Ovidrel.
What happens if I take the trigger shot at the wrong time?
Timing is critical. Taking it too early or too late can affect how many mature eggs are retrieved. If you realize you have made an error, call your clinic immediately. This is one reason many patients set multiple alarms and double-check the time with their nurse before injecting.
Will Ovidrel cause a positive pregnancy test?
Yes, Ovidrel contains hCG, the same hormone that pregnancy tests detect. Taking a home pregnancy test within 10 to 14 days after your trigger shot may show a positive result even if you are not pregnant. Your clinic will measure hCG levels at a specific time after transfer to get an accurate result.
Is Ovidrel always used as the trigger shot?
No. Some doctors use Lupron as a trigger instead, particularly for patients at high risk of OHSS. Lupron triggers produce a more natural LH surge and are associated with lower OHSS risk. Your doctor will choose the trigger approach that is safest for you.
Medical disclaimer: This page provides general educational information only. It is not medical advice and should not replace guidance from your doctor, nurse, or reproductive endocrinologist. Every person's treatment is unique. Always consult your care team before making any decisions about your medications or treatment plan.
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About the author
Viv
BSc, Patient Advocate
Founder, TrackMyIVF
I built TrackMyIVF because I needed it during my own journey. Every feature comes from real experience.